RESENT from 01/26/05, because little seems to have changed in the opinion of most doctors. Lack of b12 ……..repeated miscarriage All of you who are long on my list already got many, many articles about vitamin B12 and folic acid, concerning nearly any possible disease/medical situation. I wrote to you also about b12 and fertility and [ab] normal pregnancies. For quite a while already I am advising any woman who wants to get pregnant[ or who may become pregnant ] to get nearly routinely!! a few injections of b12 [dependent on certain medical factors, not only the blood levels] [now a day methylcobalamine tablets are available in Israel and they work fine, no injections needed any more]I am sending you an article, this time -Baruch ha-Shem-from our very “midst”.

Addition: some people need still injections and sublingual tablets-even methylcobalamine-are not always effective [enough]

[Dr. Michael Bennett of Ha’Emek Medical Center in Afula]Many patients I told about this, maybe I even sent the article once in the past. Please, print this article out for any doctor/gynaecologist you are visiting. Women may be spending 10.000 shekalim ?? on I.V.F greatments[s]and are just lacking a “few shekalim of B12″. B 12 may be also quite important to prevent spina bifida, just like folic acid. STRANGE WORLD , INDEED. Lack of Vitamin B12 Linked to Repeat Miscarriage Women who are deficient in vitamin B12 may be at risk for infertility or repeat miscarriages, but in many cases, they can change their situation with vitamin therapy, an Israeli doctor report.NEW YORK (Reuters Health / May 2, 2001) — In his study, Dr. Michael Bennett of Ha’Emek Medical Center in Afula, Israel, describes 14 women with infertility or repeated miscarriages who were deficient in vitamin B12–a rare condition. The nutrient plays a key role in the nervous system and the development of new tissue, and is also crucial in ovulation. Women who are deficient may not ovulate, for instance, or a fertilized egg may not develop, resulting in miscarriage. But according to the report in a recent issue of The Journal of Reproductive Medicine, 10 of the women conceived after beginning vitamin therapy; six of these women conceived almost immediately. Seven of the women were found to have mutations in a gene involved in metabolism of folate. That, combined with the B12 deficiency, increased their risk of thrombophilia, a condition in which they were at increased risk of clot formation. Six other women were found to have other causes of thrombophilia.One woman had suffered seven miscarriages before doctors discovered that she was deficient in vitamin B12. The woman went on to have three children once the problem was corrected.“Correcting this deficiency can rapidly lead to a normal pregnancy,” Bennett writes. “This study illustrates the importance of measuring B12 levels…in every patient investigated for infertility or recurrent miscarriage.”Five women did not conceive, however. Three of these women were at least 40 years old and decided not to try to have children, one woman lost her husband and one woman had not become pregnant after 3 years, the report indicates.SOURCE: The Journal of Reproductive Medicine 2001;46:209-212.