Those of you who have been using Rauwolfia often in the form of Mukta Vati, maybe interested in the following article.

When I finished my medical studies Rauwolfia was in fact the only good anti-hpertnsive drug and was prescribed as Reserpine [alas, not the whole herb was used]but only the active substance [to be able to patent the herb]

Antihypertensive and Antihyperlipidemic Activity of Aqueous Methanolic Extract of Rauwolfia Serpentina in Albino Rats

Show all authorsSyed Muhammad Ali ShahSyed Ali Raza NaqviNaveed Munir, …First Published July 24, 2020 Research Article Find in PubMed


Rauwolfia serpentina has a wide range of therapeutic effects so this study was planned to explore the antihypertensive and antihyperlipidemic therapeutic responses of R serpentina 

doses using albino rats by measuring the blood pressure, biochemical parameters, and histological architecture of liver and kidney tissues. Thirty albino rats were divided into 5 groups (n = 6) as G1 (normal Control) received normal diet, G2 (positive control) received only 8% NaCl added diet (high salt diet); G3 was given atenolol (standard drug control) 50 mg/kg body weight, G4 and G5 groups were given methanolic plant extract as low dose (100 mg/kg body weight) and high dose (200 mg/Kg body weight) daily along with high salt diet for 4 weeks, respectively. Rauwolfia serpentina significantly (P < .05) decreased the blood pressure in G4 and G5 groups as compared to G2 and G3. Significant (P < .05) impact was reported, on serum lipid profile and serum proteins as well as hepatoprotective and renoprotective potential on studying tissues sections under microscope, in animal groups given herbal extract as compared to control groups.

It could be concluded that R serpentina has therapeutic effect to manage the hypertension and hypercholesterolemia most probably via protecting the liver and renal architectures.