​The efficacy of a combined topical preparation with rhubarb and sage extracts FOR HERPES LABIALIS

Combined herbal preparation for topical treatment of Herpes labialis.

Forsch Komplementarmed Klass Naturheilkd. 2001 Dec;8(6):373-82.

Saller R1, Büechi S, Meyrat R, Schmidhauser C.

Author information

Departement für Innere Medizin, Naturheilkunde, Universitätsspital Zürich.



The efficacy of many preparations for topical use in herpes infections has remained rather disappointing. The development of new antiviral drugs, especially herbal preparations, thus remains desirable. In a screening study with plant extracts, a rhubarb root extract and a sage extract showed a promising activity.


………. The reference product was Zovirax cream (Zovirax(R) Creme) with the active ingredient aciclovir (50 mg/g).


The combined topical sage-rhubarb preparation proved to be as effective as topical aciclovir cream and tended to be more active than the sage cream.

Copyright 2001 S. Karger GmbH, Freiburg



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