The results indicated that PO [ Portulaca oleracea] significantly inhibits the tumor cell growth in a time- and dose- dependent manner. Additionally, these studies suggest that PO may exert its effects through anti- inflammatory properties and balancing the adaptive and innate immune system depending on situations. As mentioned previously, PO can inhibit the inflammatory states by the dominance of Th2 response such as asthma, cancer and atopic dermatitis and modulate this imbalance toward Th1 response. In contrast, the results showed that PO modulates the evoked Th1 disorders including hepatitis and multiple sclerosis. Taken together, PO is known as immuno-modulatory and anti-oxidant medicinal herb, which may be introduced for the treatment of many immunological based disorders. In addition, it could be used as a substitute for synthetic anti- oxidant in food preservation and may be potentially useful as a food and cosmetic ingredient. Meanwhile, the oxidative stress can cause hyper-sensitivities, so PSO is expected to develop a health care product for the prevention and mitigation of hyper-sensitivities symptoms. PSO is expected to show superior anti-oxidant activity and anti-tumor effects due to its high omega-3 fatty acid content. Thus, it is a good candidate as both a healthy food and cosmetic ingredient.