Epidermolysis bullosa (EB) is a rare, heterogenous genetic disorder characterized by extreme skin fragility and trauma-induced blister formation of the skin, mucosa or internal epithelial linings of organs. 

There is no good treatment known for this comdition.Current evidence indicates that birch bark extract is an effective, emerging treatment option for patients with dystrophic and junctional EB.

https://pubmed.ncbi.nlm.nih.gov/37658982/