One group received no additional treatment, a
second took 100 mg a day of aspirin, and a third
received the aspirin plus the combination of extracts of
French maritime pine bark (150 mg/day) and Centella
asiatica (450 mg/day).
At the end of the three years, more than 20% of
patients in the standard management and the aspirin
group had progressed to more severe and extensive
atherosclerotic plaque.
Among patients treated with aspirin + pine bark +
Centella, only 5.3% of patients experienced plaque
progression.