Aspirin enough for acute stroke, plavix does not add benefits ……….don’t forget MINOCYCLINE [see past articles!!]
Published in Cardiology
Journal Scan / Research · October 28, 2019
DAPT vs Aspirin Monotherapy in Acute Stroke
Stroke: A Journal of Cerebral Circulation
TAKE-HOME MESSAGE
- This study compared the effectiveness of dual antiplatelet therapy (DAPT) with clopidogrel plus aspirin with that of aspirin monotherapy (AM) in patients with acute, nonminor, and noncardioembolic stroke. A total of 2121 patients received DAPT and 2340 patients received AM. The primary outcome event (a composite of all types of stroke, MI, and all-cause mortality within 3 months of stroke onset) was not significantly different between the DAPT group and the AM group (20.9% vs 22.6%; P=.13). All-cause mortality was lower in the DAPT group (3.4% vs 4.9%; P=.02).
- DAPT, compared with AM, did not reduce risk of the primary outcome after ischemic stroke.