Parsley, a daily used culinary herb worldwide, presents enormous health benefits and through this study, it has been shown to have a remarkable antidepressant-like and anxiolytic activity, even better than classic drugs, especially with the dose of 100 mg/kg. In the search for an effective medicine with fewer or almost no side effect, this plant could be a well-placed alternative. This work encourages its daily consumption as well as its development to a well-established phytomedicine.Further research is needed to complete this work, including the performance of other behavioral tests with the same extract to confirm its efficacy. Thus, a bioguided fractionation of the phenolic extract of P. sativum is planned to identify the key component responsible for the observed anxiolytic and antidepressant-like activities and to determine their precise mechanism of action.